The operation of top homogenizer from vacuum homogenizing emulsifier machine mezclador de vacío

High-pressure homogenization

is essential to the quality and stabilization of beauty creams, lotions, nail varnishes, shampoos, toothpastes, and emulsions containing different oils since it is a very effective way to create the exact required product texture (via particle size reduction) while at the same time creates very stable product compared to the traditional devices such as agitators, stirrers, rotor-stator devices or colloid mills. This is achieved by reducing the particle size and uniformity under conditions of extreme pressure, shear and stress. The result is a homogeneous effective product with superior stability and shelf life. It is well known fact that one of the limiting factors in the performance of some cosmetic product, for instance beauty creams, is its ability to be absorbed into the skin. Drastic particle size reduction enables the skin to absorb the active ingredients in these creams as the surface area increases after the homogenization (vs volume ratio). High-pressure homogenization (also known as micronization) also ensures the most efficient use of the active agents, thus reducing product costs.

                  

A typical Very High Pressure (VHP) homogenizer for cosmetic applications includes the following:
High wear resistant parts and homogenizing valves
Two stage homogenizing valve
All wetted parts are electro-polished, final surface roughness Ra lower than 0,5µm.
Explosion proof design according to the latest American and European standards.
Biotechnology Homogenizer Applications
High-pressure homogenization is widely used for cell rupture (cell rupturing, cell disruption) applications in order to extract intra-cell substances without using solvents or other chemicals for the cell wall breakage. The main purpose is to release intercellular substances such as proteins, enzymes, and vitamins that are found in high concentrations in various organisms such as yeasts, algae and bacteria (and other biological products). High-pressure homogenizers are very effective and efficient for cell rupture operations and can often maximize the yield from valuable source material while keeping product quality at a very high level.

A typical homogenizer skid for cell rupture applications includes the following:
Very High Pressure (VHP) Homogenizer unit
Product stuffing pump
Product pooler
Hard wired or Programmable Logic Controller (PLC) based control panel
Aseptic plunger and valve seals
Aseptic seal water condenser
Clean- in-Place (CIP) and Sterilize-in-Place SIP-able
cGMP compliant validation documentation package
Complete Factory Acceptance Test (FAT) and Site Acceptance Test.
The skid systems are built to the requirements of the ASME BPE standards, and Niro Soavi manufactures the homogenizer units in compliance with the ISO 9001 QA program.

Pharmaceutical Homogenizer Applications
Homogenization (known in the pharmaceutical industry as micronization) is the process of reducing the particle sizes of pharmaceutical products, under very high pressures, sheer, turbulence, acceleration and impact, to make them more stable and clinically effective. The bioavailability of the product increases and the tolerance of some otherwise borderline drugs can improve.
The emulsion, suspension or solution is pumped into the high-pressure homogenizer after which it is forced through a special homogenization valve at extremely high pressures (up to 1,500 bar per 21,750). The particles enter the homogenizer with 500 µm maximum sizes, after the treatment the large particles are dispersed and reduced, the particle size typically range from 0.4 to 1 micron depending on the specific application.
High-pressure homogenization in the pharmaceutical industry has proven its ability to make more stable product, with better active ingredient dispersion, than has been achieved with conventional stirrers, rotor-stator devices or colloid mills. It achieves this by reducing the particle size and uniformity under conditions of extreme pressure and stress. The result is a more clinically effective product with greater stability and shelf life.

Shenzhen Penglai since 1992 has been manufacturing the cosmetic&food making and packaging machinery.In these field we have the experience rich enough to solve the questions encountered by our customers from both home and abroad.For more information about high quality machinery like the operation of top homogenizer from vacuum homogenizing emulsifier machine mezclador de vacío  ,please email via jackdu999@yahoo.com or browse our website www.cosmeticmakingmachine.com
Follow us on twitter:http://www.twitter.com/jackdu007
Like us on facebook:http://www.facebook.com/jackdu999
Skype us by :turnanewleaf
Tel:+86-158-11882441 PENGLAI INDUSTRIAL CORPORATION LIMITED